Platelet-rich fibrin in endodontics

Clinical Articles , Current Issue

Dr. Edward S. Lee discusses a tissue-engineering material with a variety of applications

Introduction

Platelet-rich fibrin (PRF) is a bioactive material made from the centrifugation of a patient’s whole blood. It is a second-generation platelet concentrate first described by Choukroun1 and is used to accelerate soft and hard tissue healing. This simplified and cost-effective chairside procedure results in a resorbable fibrin matrix enriched with platelets and leukocytes.